Diagnostics (Mar 2021)

Differential Diagnosis between Oral Metastasis of Renal Cell Carcinoma and Salivary Gland Cancer

  • Yoshihiro Morita,
  • Kana Kashima,
  • Mao Suzuki,
  • Hiroko Kinosada,
  • Akari Teramoto,
  • Yuka Matsumiya,
  • Narikazu Uzawa

DOI
https://doi.org/10.3390/diagnostics11030506
Journal volume & issue
Vol. 11, no. 3
p. 506

Abstract

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Renal cell carcinoma, which has clear cells in 70% of cases, has a high frequency of hematogenous distant metastases to lung, bone, liver, and other areas. Metastatic cancer accounts for 1 to 3% of malignant tumors in the stomatognathic region, and the metastasis of renal cell carcinoma to the oral mucosal tissue, though extremely rare, does occur. In addition, clear cells have been observed in some salivary gland cancers in the oral cavity. Therefore, the differential diagnosis of metastatic renal cell carcinoma and salivary gland cancer is important. This review discusses the differential diagnosis between metastatic renal cell carcinoma and malignant tumors of the salivary gland.

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