Emerging Infectious Diseases (May 2024)

Novel Variant and Known Mutation in 23S rRNA Gene of Mycoplasma pneumoniae, Northern Vietnam, 2023

  • Dinh-Dung Nguyen,
  • Nhan Thi Ho,
  • Lynn G. Dover,
  • Anh Hang Mai Vo,
  • Ha Thi Thanh Ly,
  • Phuong Mai Doan,
  • Hang Thi Nguyen,
  • Nguyen Thi Thao Luu,
  • An Nhat Pham,
  • Huyen Thi Thanh Tran

DOI
https://doi.org/10.3201/eid3005.231632
Journal volume & issue
Vol. 30, no. 5
pp. 1034 – 1036

Abstract

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During a 2023 outbreak of Mycoplasma pneumoniae–associated community-acquired pneumonia among children in northern Vietnam, we analyzed M. pneumoniae isolated from nasopharyngeal samples. In almost half (6 of 13) of samples tested, we found known A2063G mutations (macrolide resistance) and a novel C2353T variant on the 23S rRNA gene.

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