The use of CRP / albumin ratio as an indicator of severe COVID-19 disease in intensive care units

Abstract

COVID-19 disease is an infectious disease that has been spriding worldwide. The effect of this disease is more severe in some people and as scuh coushing many deaths. CRP and albumin are biomarkers known to be associated with mortality in COVID-19 patients. In addition, it has many advantages such as its usage in many hospitals and providing relatively quick results. We aimed to test the diagnostic power of the CRP / Albumin ratio in indicating severe disease in this patient group. 174 patients hospitalized between March 30 and December 31 , 2020, were included in the study. The demographic data of the patients and CRP , albumin and CRP/Albumin ratio other laboratory results were recorded by scanning the patient files. Follow-up patients with and without invasive mechanical ventilation were grouped. In comparing between the groups, the rate of two or more comorbidities was higher in the patient group who received invasive mechanical ventilation support. While the CRP value was higher in these patients, the albumin value was lower. There is a statistically significant correlation between the CRP / albumin ratio and the application of invasive mechanical ventilation support. CRP and albumin are parameters that are widely considered in the COVID-19 patient group and evaluated in the laboratory in many hospitals. The test is relatively inexpensive and easy to apply.Serum levels can change for various reasons. As these biomarkers are used alone as indicators of mortality, the CPR / albumin ratio can be considered one of the early indicators of the need for invasive mechanical ventilation in the covid-19 patient group. [Med-Science 2022; 11(1.000): 228-32]

Keywords

• covid-19,crp/albumin ratio,mechanical ventilation