mBio (Jun 2021)
Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate
- Kimberly K. Kajihara,
- Homer Pantua,
- Hilda Hernandez-Barry,
- Meredith Hazen,
- Kiran Deshmukh,
- Nancy Chiang,
- Rachana Ohri,
- Erick R. Castellanos,
- Lynn Martin,
- Marissa L. Matsumoto,
- Jian Payandeh,
- Kelly M. Storek,
- Kellen Schneider,
- Peter A. Smith,
- Michael F. T. Koehler,
- Siao Ping Tsai,
- Richard Vandlen,
- Kelly M. Loyet,
- Gerald Nakamura,
- Thomas Pillow,
- Dhaya Seshasayee,
- Sharookh B. Kapadia,
- Wouter L. W. Hazenbos
Affiliations
- Kimberly K. Kajihara
- ORCiD
- Department of Infectious Diseases, Genentech, Inc., South San Francisco, California, USA
- Homer Pantua
- ORCiD
- Department of Infectious Diseases, Genentech, Inc., South San Francisco, California, USA
- Hilda Hernandez-Barry
- ORCiD
- Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, California, USA
- Meredith Hazen
- ORCiD
- Department of Antibody Engineering, Genentech, Inc., South San Francisco, California, USA
- Kiran Deshmukh
- ORCiD
- Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, California, USA
- Nancy Chiang
- ORCiD
- Department of Antibody Engineering, Genentech, Inc., South San Francisco, California, USA
- Rachana Ohri
- ORCiD
- Department of Protein Chemistry, Genentech, Inc., South San Francisco, California, USA
- Erick R. Castellanos
- ORCiD
- Department of Structural Biology, Genentech, Inc., South San Francisco, California, USA
- Lynn Martin
- ORCiD
- Department of BioMolecular Resources, Genentech, Inc., South San Francisco, California, USA
- Marissa L. Matsumoto
- ORCiD
- Department of Structural Biology, Genentech, Inc., South San Francisco, California, USA
- Jian Payandeh
- ORCiD
- Department of Infectious Diseases, Genentech, Inc., South San Francisco, California, USA
- Kelly M. Storek
- ORCiD
- Department of Infectious Diseases, Genentech, Inc., South San Francisco, California, USA
- Kellen Schneider
- ORCiD
- Department of Antibody Engineering, Genentech, Inc., South San Francisco, California, USA
- Peter A. Smith
- ORCiD
- Department of Infectious Diseases, Genentech, Inc., South San Francisco, California, USA
- Michael F. T. Koehler
- ORCiD
- Department of Medicinal Chemistry; Genentech, Inc., South San Francisco, California, USA
- Siao Ping Tsai
- ORCiD
- Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, California, USA
- Richard Vandlen
- ORCiD
- Department of Protein Chemistry, Genentech, Inc., South San Francisco, California, USA
- Kelly M. Loyet
- ORCiD
- Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, California, USA
- Gerald Nakamura
- ORCiD
- Department of Antibody Engineering, Genentech, Inc., South San Francisco, California, USA
- Thomas Pillow
- ORCiD
- Department of Medicinal Chemistry; Genentech, Inc., South San Francisco, California, USA
- Dhaya Seshasayee
- ORCiD
- Department of Antibody Engineering, Genentech, Inc., South San Francisco, California, USA
- Sharookh B. Kapadia
- ORCiD
- Department of Infectious Diseases, Genentech, Inc., South San Francisco, California, USA
- Wouter L. W. Hazenbos
- ORCiD
- Department of Infectious Diseases, Genentech, Inc., South San Francisco, California, USA
- DOI
- https://doi.org/10.1128/mBio.00202-21
- Journal volume & issue
-
Vol. 12,
no. 3
Abstract
Antibiotic treatment of life-threatening P. aeruginosain vitroP. aeruginosa
