High-throughput analysis of DNA repair in microplates towards identification of inhibitors

Abstract

Abstract Environmental factors can inhibit DNA repair and cause indirect mutagenic actions. Here the author introduces a recent paper on a novel high-throughput system to analyze the various enzymatic activities involved in base excision repair. Such systems will facilitate the identification of compounds that suppressively affect DNA repair.

Keywords

• DNA repair
• Base excision repair
• High-throughput analysis