European Journal of Medical Research (Apr 2025)

The impact of environmental factors on respiratory tract microbiome and respiratory system diseases

  • Yutao Ge,
  • Guo Tang,
  • Yawen Fu,
  • Peng Deng,
  • Rong Yao

DOI
https://doi.org/10.1186/s40001-025-02517-3
Journal volume & issue
Vol. 30, no. 1
pp. 1 – 8

Abstract

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Abstract The respiratory tract microbiome, a complex ecosystem of microorganisms colonizing the respiratory mucous layers and epithelial surfaces along with their associated microenvironment, plays a vital role in maintaining respiratory function and promoting the maturation of the respiratory immune system. Current research suggests that environmental changes can disrupt the respiratory microbiota, potentially leading to disease. This review summarizes existing research on the impact of environmental factors on the respiratory microbiome and associated diseases, aiming to offer new insights into the prevention and treatment of respiratory disease.

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