Respiratory papillomatosis with small cell carcinoma: case report and brief review

Abstract

Respiratory Papillomatosis is a rare disease in which multiple exophytic squamous wart-like lesions occur within the respiratory tract. Recurrent Respiratory Papillomatosis (RRP) has the potential for malignant transformation to squamous lung cell carcinoma with a dismal prognosis. Most of the prior literature has shown malignant transformation of respiratory papillomatosis into squamous cell carcinoma. Here, we report a rare presentation of respiratory papillomatosis coexisting with small cell carcinoma and a review of relevant literature.

Keywords

• papillomatosis
• invasion
• small cell carcinoma
• squamous cell carcinoma
• hpv 11
• chest x-ray
• ct scan
• bronchoscopy
• endobronchial mass
• p53
• prb
• p21waf1