Acute Kidney Injury after Endoscopic Retrograde Cholangiopancreatography—A Hospital-Based Prospective Observational Study
Florica Gadalean,
Florina Parv,
Oana Milas,
Ligia Petrica,
Iulia Ratiu,
Bogdan Miutescu,
Adrian Goldis,
Cristina Gluhovschi,
Flaviu Bob,
Anca Simulescu,
Mihaela Patruica,
Adrian Apostol,
Viviana Ivan,
Adalbert Schiller,
Daniela Radu
Affiliations
Florica Gadalean
Department of Internal Medicine II—Division of Nephrology, “Victor Babeș” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania
Florina Parv
County Emergency Hospital Timisoara, 300723 Timisoara, Romania
Oana Milas
Department of Internal Medicine II—Division of Nephrology, “Victor Babeș” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania
Ligia Petrica
Department of Internal Medicine II—Division of Nephrology, “Victor Babeș” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania
Iulia Ratiu
County Emergency Hospital Timisoara, 300723 Timisoara, Romania
Bogdan Miutescu
County Emergency Hospital Timisoara, 300723 Timisoara, Romania
Adrian Goldis
County Emergency Hospital Timisoara, 300723 Timisoara, Romania
Cristina Gluhovschi
Department of Internal Medicine II—Division of Nephrology, “Victor Babeș” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania
Flaviu Bob
Department of Internal Medicine II—Division of Nephrology, “Victor Babeș” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania
Anca Simulescu
Department of Internal Medicine II—Division of Nephrology, “Victor Babeș” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania
Mihaela Patruica
Department of Internal Medicine II—Division of Nephrology, “Victor Babeș” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania
Adrian Apostol
County Emergency Hospital Timisoara, 300723 Timisoara, Romania
Viviana Ivan
County Emergency Hospital Timisoara, 300723 Timisoara, Romania
Adalbert Schiller
Department of Internal Medicine II—Division of Nephrology, “Victor Babeș” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania
Daniela Radu
County Emergency Hospital Timisoara, 300723 Timisoara, Romania
Background: Endoscopic retrograde cholangiopancreatography (ERCP) represents a major pivotal point in gastrointestinal endoscopy. Little is known about acute kidney injury (AKI) post-ERCP. This study analyses the incidence, risk factors, and prognosis of post-ERCP AKI. Methods: A total of 396 patients were prospectively studied. AKI was defined by an increase in serum creatinine (SCr) ≥ 0.3 mg/dL or by an increase in SCr ≥ 50% in the first 48 h post-ERCP. Logistic regression analysis was used to identify the predictors of AKI and in-hospital mortality. A two-tailed p value p p = 0.006), choledocholithiasis (aOR = 4.05, 95% CI: 1.98–8.29, p p p p p < 0.013). Conclusions: Post-ERCP AKI represented an important complication associated with longer hospital stay. Moderate-to-severe post-ERCP AKI was an independent risk factor for in-hospital mortality.
