Construction and activity analyses of single functional mouse peroxiredoxin 6 (Prdx6)

Abstract

Introduction: Peroxiredoxin 6 (Prdx6) is a bifunctional protein with glutathione peroxidase activity and phospholipase A2 activity. Previous studies have shown a significant positive correlation between the intracellular survival ability of Brucella and Prdx6. Here, the Prdx6 enzyme with a single activity was constructed to facilitate study of the relationship between the single function of Prdx6 and Brucella infection.

Keywords

• mouse
• peroxiredoxin 6
• glutathione peroxidase
• phospholipase a2
• soe-pcr