Life (Nov 2021)

Build-a-Cell: Engineering a Synthetic Cell Community

  • Caroline Frischmon,
  • Carlise Sorenson,
  • Michael Winikoff,
  • Katarzyna P. Adamala

DOI
https://doi.org/10.3390/life11111176
Journal volume & issue
Vol. 11, no. 11
p. 1176

Abstract

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Build-a-Cell is a global network of researchers that aims to develop synthetic living cells within the next decade. These cells will revolutionize the biotechnology industry by providing scientists and engineers with a more complete understanding of biology. Researchers can already replicate many cellular functions individually, but combining them into a single cell remains a significant challenge. This integration step will require the type of large-scale collaboration made possible by Build-a-Cell’s open, collective structure. Beyond the lab, Build-a-Cell addresses policy issues and biosecurity concerns associated with synthetic cells. The following review discusses Build-a-Cell’s history, function, and goals.

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