Neurotropic enteroviruses (Picornaviridae: <i>Enterovirus</i>): predominant types, basis of neurovirulence

Abstract

Enteroviruses are one of the most common causative agents of infectious diseases of the central nervous system. They are characterized by genetic variability, the ability to infect a wide range of cells, including brain microglial cells and astrocytes, and persist in the central nervous system tissue, causing delayed and chronic diseases. The review presents data on the basis of neurovirulence of non-polio enteroviruses and the most common pathogens causing enteroviral neuroinfections.

Keywords

• non-polio enteroviruses
• enteroviral neuroinfections
• serous meningitis
• acute flaccid paralysis