Nature Communications (Nov 2021)

Risk-stratification of febrile African children at risk of sepsis using sTREM-1 as basis for a rapid triage test

  • Aleksandra Leligdowicz,
  • Andrea L. Conroy,
  • Michael Hawkes,
  • Melissa Richard-Greenblatt,
  • Kathleen Zhong,
  • Robert O. Opoka,
  • Sophie Namasopo,
  • David Bell,
  • W. Conrad Liles,
  • Bruno R. da Costa,
  • Peter Jüni,
  • Kevin C. Kain

DOI
https://doi.org/10.1038/s41467-021-27215-6
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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Identification of febrile children at risk of death in low-resource settings can improve survival, but tools for their prompt recognition are lacking. Here, the authors show that sTREM-1 measured at clinical presentation predicts in-hospital mortality in febrile children in Uganda.