Patient Preference and Adherence (Jun 2024)

Assessment of Health-Related Quality of Life Among Patients with Chronic Diseases and Its Relationship with Multimorbidity: A Cross-Sectional Study from Saudi Arabia

  • Alzarea AI,
  • Khan YH,
  • Alzarea SI,
  • Alanazi AS,
  • Alsaidan OA,
  • Alrowily MJ,
  • Al-Shammari M,
  • Almalki ZS,
  • Algarni MA,
  • Mallhi TH

Journal volume & issue
Vol. Volume 18
pp. 1077 – 1094

Abstract

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Abdulaziz Ibrahim Alzarea,1 Yusra Habib Khan,1 Sami I Alzarea,2 Abdullah Salah Alanazi,1 Omar Awad Alsaidan,3 Maily J Alrowily,4 Monefah Al-Shammari,5 Ziyad Saeed Almalki,6 Majed A Algarni,7 Tauqeer Hussain Mallhi1 1Department of Clinical Pharmacy, College of Pharmacy, Jouf University, Sakaka, Al-Jouf, Saudi Arabia; 2Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Al-Jouf, Saudi Arabia; 3Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Al-Jouf, Saudi Arabia; 4Department of Radiology, Aljouf Health Cluster, Domat Al-Jandal, Al-Jouf, Saudi Arabia; 5Domat Al-Jandal General Hospital, Aljouf Health Cluster, Domat Al Jandal, Al-Jouf, Saudi Arabia; 6Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia; 7Department of Clinical pharmacy, College of pharmacy, Taif university, Taif, Saudi ArabiaCorrespondence: Abdulaziz Ibrahim Alzarea; Tauqeer Hussain Mallhi, Email [email protected]; [email protected]: Chronic diseases hold the potential to worsen the overall health of patients by limiting their functional status, productivity, and capacity to live well, affecting their overall health-related quality of life (HRQoL). The purpose of the study was to assess the HRQoL of individuals with chronic diseases residing in the Al-Jouf region of Saudi Arabia. Furthermore, the current study also sought to ascertain the impact of multimorbidity and the duration of illness on HRQoL.Material and Methods: A cross-sectional study was conducted among the residents of Al-Jouf region for a period of 6 months. A self-administered EuroQoL (EQ-5D-5L) study tool was used. Appropriate statistical analysis was conducted to ascertain the relationship between various variables and HRQoL.Results: A total of 500 out of 562 participants completed the study, with a response rate of 88.97%. Participants had a mean age of 46.15 ± 16.79 years, and the majority were female (n = 299; 59.80%). A mean HRQoL score of 0.82 ± 0.20 was reported, poorest in patients with kidney failure (0.65 ± 0.26) and highest in hepatitis. However, nearly half of the participants had diabetes mellitus type II (n = 205, 39.20%). Patients aged < 30 years (OR: 0.109; p = 0.002), male participants (OR: 0.053; p < 0.001), no disability (OR: 0.143; p = 0.002), and < 2 comorbid diseases (0.84 ± 0.18; p < 0.001) reported better QoL. Additionally, comorbid conditions such as DM, prolong the duration of the overall illness (14.19 ± 7.67 years). Overall, imperfect health (n = 390, 78%) was reported by the study participants.Conclusion: The present study provided preliminary data about the current HRQoL status of individuals with imperfect health and lower HRQoL. In the future, large-scale longitudinal studies are required to investigate the most prevalent chronic diseases, their associations, and change in HRQoL, as there is a dearth of information in the Saudi population.Keywords: HRQoL, EQ-5D-5L, chronic diseases, diabetes mellitus, hypertension, Saudi Arabia, disease outcomes, quality of life

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