Tomography
(Sep 2022)
Prostate Cancer Biochemical Recurrence Resulted Negative on [<sup>68</sup>Ga]Ga-PSMA-11 but Positive on [<sup>18</sup>F]Fluoromethylcholine PET/CT
Riccardo Laudicella,
Flavia La Torre,
Valerio Davì,
Ludovica Crocè,
Demetrio Aricò,
Giuseppe Leonardi,
Simona Russo,
Fabio Minutoli,
Irene A. Burger,
Sergio Baldari
Affiliations
Riccardo Laudicella
Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Flavia La Torre
Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Valerio Davì
Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Ludovica Crocè
Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Demetrio Aricò
Department of Nuclear Medicine, Humanitas Oncological Centre of Catania, 95125 Catania, Italy
Giuseppe Leonardi
Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Simona Russo
Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Fabio Minutoli
Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Irene A. Burger
Department of Nuclear Medicine, University Hospital Zürich, University of Zürich, 8091 Zürich, Switzerland
Sergio Baldari
Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
DOI
https://doi.org/10.3390/tomography8050205
Journal volume & issue
Vol. 8,
no. 5
pp.
2471
– 2474
Abstract
Read online
For prostate cancer (PCa) biochemical recurrence (BCR), the primarily suggested imaging technique by the European Association of Urology (EAU) guidelines is prostate-specific membrane antigen (PSMA) positron emission tomography/computer tomography (PET/CT). Indeed, the increased detection rate of PSMA PET/CT for early BCR has led to a fast and wide acceptance of this novel technology. However, PCa is a very heterogeneous disease, not always easily assessable with the highly specific PSMA PET with around 10% of cases occuring without PSMA expression. In this paper, we present the case of a patient with PCa BCR that resulted negative on [68Ga]Ga-PSMA-11 PET/CT, but positive on [18F]Fluoromethylcholine (Choline) PET/CT.
Keywords
Published in Tomography
ISSN
2379-1381 (Print)
2379-139X (Online)
Publisher
MDPI AG
Country of publisher
Switzerland
LCC subjects
Medicine: Medicine (General): Computer applications to medicine. Medical informatics
Website
https://www.mdpi.com/journal/tomography
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