Familial left ventricular noncompaction cardiomyopathy due to a novel mutation in the MYH 7 gene

Abstract

Left Ventricular Non Compaction (LVNC) is considered a unique cardiomyopathy according to the American Heart Association guidelines. The genetic ethology of LVNC in children is not completely understood although upto 41% of LVNC are thought to be genetic. We report a family with LVNC due to a novel mutation in the MYH 7 gene.

Keywords

• genetic cardiomyopathy
• left ventricular noncompaction
• massive parallel sequencing