Nature Communications (May 2016)

Argonaute-associated short introns are a novel class of gene regulators

  • Thomas B. Hansen,
  • Morten T. Venø,
  • Trine I. Jensen,
  • Anne Schaefer,
  • Christian K. Damgaard,
  • Jørgen Kjems

DOI
https://doi.org/10.1038/ncomms11538
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 10

Abstract

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MicroRNAs are important small regulatory RNAs produced by sequential Drosha and Dicer cleavage. Here the authors describe 'agotrons', a subclass of small RNAs that bypass the canonical biogenesis machinery.