Nature Communications (Aug 2018)

Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia

  • V. Bansal,
  • M. Mitjans,
  • C. A. P. Burik,
  • R. K. Linnér,
  • A. Okbay,
  • C. A. Rietveld,
  • M. Begemann,
  • S. Bonn,
  • S. Ripke,
  • R. de Vlaming,
  • M. G. Nivard,
  • H. Ehrenreich,
  • P. D. Koellinger

DOI
https://doi.org/10.1038/s41467-018-05510-z
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 12

Abstract

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Educational attainment and schizophrenia have a negative phenotypic relationship but show positive genetic correlation. Here, the authors study genetic dependence between the two traits and find that multiple genes have pleiotropic effects on both without a systematic pattern of sign concordance.