Synthesis and Identification of Triorganotin (IV)-Tyrosine Complexes and Study Their Applications as Antioxidant by DPPH and CUPRAC Methods.

Abstract

Abstract Through condensation reactions between tyrosine (ligand) and triorganotin (IV) chloride salts in the presence of sodium hydroxide, three triorganotin (IV)-tyrosine complexes were successfully synthesized. All the components were dissolved in methanol and refluxed for five hours. The produced complexes were characterized by elemental analysis (CHN), Fourier transform infrared spectroscopy and nuclear magnetic resonance spectroscopy (1H, 13C and 119Sn-NMR). Based on spectrum measurements, trigonal bipyramidal geometries for the complexes produced in yields of 85–97% were assigned. Using the DPPH and CUPRAC methods, this study examined the antioxidant activity of tri organotin (IV)-tyrosine complexes. Due to the metal moiety, organotin (IV) complexes had more antioxidant activity than ligands, whereas trimethyl tin (IV) complex showed a higher level of antioxidant activity than other complexes.

Keywords

• فعالية مضادات الأكسدة, تفاعل التكثيف, طريقة CUPRAC, معقدات ثلاثية عضوية للقصدير- تايروسين, تايروسين.