Patients with severe cutaneous adverse drug reactions have extremely high hair cortisol concentrations that do not correlate with the presence of depression

• Eddy M. Zitha, MSc, MD,
• Ogheneochuko U. Oputu, PhD,
• Sthomo Mevana, ND, BTECH,
• Bukiwe Thwala, MPH,
• Lovemore Mapahla, MSc,
• Aneliswa Mpungose, BCMP,
• Thuraya Isaacs, MD, MFamMed, MMed,
• Jonny Peter, MD, PhD,
• Rannakoe J. Lehloenya, BSc, MD,
• Nonhlanhla P. Khumalo, MD, PhD

Affiliations

Eddy M. Zitha, MSc, MD

Division of Dermatology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Ogheneochuko U. Oputu, PhD

Hair and Skin Research Laboratory, Groote Schuur Hospital, Division of Dermatology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Sthomo Mevana, ND, BTECH

Hair and Skin Research Laboratory, Groote Schuur Hospital, Division of Dermatology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Bukiwe Thwala, MPH

Division of Allergy and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Lovemore Mapahla, MSc

The Modelling and Simulation Hub, Africa, Department of Statistical Sciences, University of Cape Town, Cape Town, South Africa; Division of Epidemiology and Biostatistics, Global Health Department, Stellenbosch University, Cape Town, South Africa

Aneliswa Mpungose, BCMP

Division of Allergy and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Thuraya Isaacs, MD, MFamMed, MMed

Division of Dermatology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Jonny Peter, MD, PhD

Division of Allergy and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Rannakoe J. Lehloenya, BSc, MD

Division of Dermatology, Department of Medicine, University of Cape Town, Cape Town, South Africa; Correspondence to: Rannakoe J. Lehloenya, BSc, MD, Dermatology Ward G23, New Groote Schuur Hospital, Anzio Road, Observatory, Cape Town 7925, South Africa

Nonhlanhla P. Khumalo, MD, PhD

Hair and Skin Research Laboratory, Groote Schuur Hospital, Division of Dermatology, Department of Medicine, University of Cape Town, Cape Town, South Africa