P405: INHIBITION OF CKS1-DEPENDENT PROTEOSTASIS REVEALS VULNERABILITIES IN LEUKAEMIC STEM CELLS WITH CONCOMITANT PROTECTION OF HEALTHY HAEMATOPOIETIC STEM CELLS

• W. Grey,
• A. Rio-Machin,
• P. Casado-Izquierdo,
• E. Gronroos,
• S. Ali,
• J. Miettinen,
• F. Bewicke-Copley,
• A. Parsons,
• C. Heckman,
• C. Swanton,
• P. Cutillas,
• J. Gribben,
• J. Fitzgibbon,
• D. Bonnet

Affiliations

W. Grey

1 York Biomedical Research Institute, The University of York, York

A. Rio-Machin

3 Bart’s Cancer Institute, London, United Kingdom

P. Casado-Izquierdo

3 Bart’s Cancer Institute, London, United Kingdom

E. Gronroos

2 The Francis Crick Institute

S. Ali

2 The Francis Crick Institute

J. Miettinen

4 HiLIFE, Helsinki, Finland

F. Bewicke-Copley

3 Bart’s Cancer Institute, London, United Kingdom

A. Parsons

4 HiLIFE, Helsinki, Finland

C. Heckman

4 HiLIFE, Helsinki, Finland

C. Swanton

2 The Francis Crick Institute

P. Cutillas

3 Bart’s Cancer Institute, London, United Kingdom

J. Gribben

3 Bart’s Cancer Institute, London, United Kingdom

J. Fitzgibbon

3 Bart’s Cancer Institute, London, United Kingdom

D. Bonnet

2 The Francis Crick Institute