Antibiotic resistance pattern of uropathogens: An experience from north Indian cancer patient

Abstract

Empirical treatment of urinary tract infections (UTIs) can be made evidence based if it is governed by the resistance pattern of common uropathogens. A retrospective study was carried out at a tertiary care cancer institute to identify the common uropathogens and to know their resistance profile. 20.82% of the outpatients′ urine samples (community-acquired urinary tract infection (CA-UTI)) and 24.83% of the indoor patients′ urine samples (hospital-acquired urinary tract infection (HA-UTI)) grew uropathogens. Escherichia coli was the predominant pathogen both in CA-UTI (68%) and HA-UTI (45%) followed by Klebsiella spp and Enterococcus spp. High level of resistance to fluoroquinolones and third generation cephalosporins was noted. Nitrofurantoin was found to be a reliable oral drug for treatment of most of the uropathogens.

Keywords

• Antibiotic resistance
• Community acquired
• Hospital acquired
• Urinary tract infection
• Uropathogens