Nature Communications (Feb 2018)
Polyrotaxane-based supramolecular theranostics
- Guocan Yu,
- Zhen Yang,
- Xiao Fu,
- Bryant C. Yung,
- Jie Yang,
- Zhengwei Mao,
- Li Shao,
- Bin Hua,
- Yijing Liu,
- Fuwu Zhang,
- Quli Fan,
- Sheng Wang,
- Orit Jacobson,
- Albert Jin,
- Changyou Gao,
- Xiaoying Tang,
- Feihe Huang,
- Xiaoyuan Chen
Affiliations
- Guocan Yu
- Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health
- Zhen Yang
- Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health
- Xiao Fu
- Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health
- Bryant C. Yung
- Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health
- Jie Yang
- State Key Laboratory of Chemical Engineering, Centre for Chemistry of High-Performance & Novel Materials, Department of Chemistry, Zhejiang University
- Zhengwei Mao
- MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University
- Li Shao
- State Key Laboratory of Chemical Engineering, Centre for Chemistry of High-Performance & Novel Materials, Department of Chemistry, Zhejiang University
- Bin Hua
- State Key Laboratory of Chemical Engineering, Centre for Chemistry of High-Performance & Novel Materials, Department of Chemistry, Zhejiang University
- Yijing Liu
- Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health
- Fuwu Zhang
- Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health
- Quli Fan
- Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Centre for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications
- Sheng Wang
- Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health
- Orit Jacobson
- Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health
- Albert Jin
- Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health
- Changyou Gao
- MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University
- Xiaoying Tang
- School of Life Science, Beijing Institute of Technology
- Feihe Huang
- State Key Laboratory of Chemical Engineering, Centre for Chemistry of High-Performance & Novel Materials, Department of Chemistry, Zhejiang University
- Xiaoyuan Chen
- Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health
- DOI
- https://doi.org/10.1038/s41467-018-03119-w
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 13
Abstract
Multifunctional nanomedicine platforms are highly promising for anticancer therapy. Here, the authors design polyrotaxane-based theranostic nanoparticles that combine targeted drug delivery with photothermal behaviour to exhibit potent anti-tumour effects in vivo.
