CD30‐positive lymphomatous (nonleukemic) variant of adult T‐cell leukemia/lymphoma, HTLV‐1 associated

Abstract

Abstract Nonleukemic variant of HTLV‐1‐associated adult T‐cell leukemia lymphoma (ATLL) is a rare variant, and herein, we describe a case with strong and diffuse positivity of neoplastic cells for CD30. Even though ATLL is aggressive entity with poor prognosis, in our case, there was very good clinical response achieved with brentuximab‐containing regimen. Therefore, HTLV‐1‐associated ATLL can be included in the differential diagnostic approach of CD30‐positive lymphoproliferative disorders.

Keywords

• adult T‐cell leukemia/lymphoma
• CD30
• HTLV‐1
• lymphomatous variant