European Journal of Case Reports in Internal Medicine (Mar 2022)

Serotonin Surge: Intravenous Escitalopram as a Rare Cause of Drug-Induced Aplastic Anaemia

  • Murtaza Hussain,
  • Katherine Boyer,
  • Anoosha Ponnapalli,
  • Dominic Awuah,
  • Sina Khaneki,
  • Smit Deliwala,
  • Ghassan Bachuwa

DOI
https://doi.org/10.12890/2022_003228

Abstract

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Escitalopram is a commonly prescribed medication that has infrequently been implicated in drug-induced thrombocytopenia (DITP) but has never been associated with aplastic anaemia in the literature. We present an extremely rare case of hypoproliferative pancytopenia due to self-administered intravenous (IV) injection of escitalopram. The crux of this case is the unusual trilineage cytopenia. Our patient was managed with steroids and supportive care with subsequent clinical and blood count recovery. This case sheds light on this uncommon but important association.

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