Central Nervous System Brucellosis Granuloma and White Matter Disease in Immunocompromised Patient

Abstract

Brucellosis is a multisystem zoonotic disease. We report an unusual case of neurobrucellosis with seizures in an immunocompromised patient in Saudi Arabia who underwent renal transplantation. Magnetic resonance imaging of the brain showed diffuse white matter lesions. Serum and cerebrospinal fluid were positive for Brucella sp. Granuloma was detected in a brain biopsy specimen.

Keywords

• central nervous system
• brucellosis
• neurobrucellosis
• Brucella
• bacteria
• white matter disease