Condition and perspective of renal replacement therapy (RRT) in children in the Republic of Belarus

Abstract

Objective: to assess the incidence, prevalence and outcomes of end-stage renal disease (ESRD) in children in Belarus, age and gender of patients, etiology of renal diseases leading to ESRD. The study included 121 children, who received RRT as of January 01, 2007 and all subsequent new patients, who started this therapy before December 31, 2016. Results. The incidence of ESRD in children in Belarus aged 0–14 years for the period 2007–2016 was 7 (6; 8) cases per year (4.8 (4.2; 5.2) per million age related population (pmarp)) and at the age of 0–17 years for the period 2009–2016 – 11 (9; 12) cases per year (5.6 (4.8; 6.8) pmarp). The prevalence of ESRD during the period from 2007 to 2016 increased by 31.7% in the group of 0–14 years [from 26 patients (18.3 pmarp) to 38 (24.1 pmarp) patients], and by 46.7% aged 0–17 [from 37 (21 pmarp) to 57 (30.8 pmarp)]. The main cause of ESRD was congenital abnormality of kidneys and urinary tract (44.6% of cases). As of December 31, 2016, 75.4% of children were transplanted, 15.8% received peritoneal dialysis and 8.8% – hemodialysis. 5 year RRT mortality rate was 17.9 deaths per 1000 patient-years and main course of death was infection complications (50%). Conclusions. The incidence of ESRD in children in Belarus corresponds to the average of ESPN/ERA–EDTA Register, the prevalence islower, but with a constant growth. The low mortality rate of patients on RRT and high transplantation activity with insufficient number of preemptive transplantations is maintained.

Keywords

• дети
• терминальная почечная недостаточность
• встречаемость
• распространенность
• летальность
• трансплантация
• перитонеальный диализ
• гемодиализ