E3S Web of Conferences (Jan 2020)

Study on the anticancer biological mechanism of Resveratrol

  • Du Juan,
  • Yang Dongsheng,
  • Hu Wenzhong,
  • Meng Fanxin,
  • Lin Zhongping

DOI
https://doi.org/10.1051/e3sconf/202021803002
Journal volume & issue
Vol. 218
p. 03002

Abstract

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Trans 3, 4 ′, 5-3 hydroxy 2 styrene (resveratrol) is a kind of naturally occurring polyphenols phytoalexin. Resveratrol has significant anti-cancer activity, mainly exists in grapes, berries, and peanuts, has anti-aging, protect the heart, antioxidant, antiproliferation, promote apoptosis and immune regulation. Resveratrol has been widely concerned in the treatment of cancer and autoimmune diseases resveratrol. Resveratrol synthase (RS) is a key enzyme in the synthesis of resveratrol synthase. In this study, RS containing genes were placed under the control of fruit-specific promoter RJ39 to transform tomatoes by transgenic method. The extraction of fruits containing RS genes showed an obvious absorption peak on the HPLC chromatographic map, and it also had an obvious inhibitory effect on the growth of Hela cells.