Impact of Vitamin D Supplementation in the Therapy Of Tuberculosis

Abstract

Ultraviolet B (UV-B) synthesis occurs when the skin is exposed to sunshine and produces vitamin D as a result. Additionally, nutritional supplements and diet can provide it. Animals are the primary source of vitamin D. Vitamin D has been identified as a risk factor for tuberculosis (TB) disease and infection. It is considered that vitamin D influences the release of antimicrobial peptides like cathelicidin in response to viral and bacterial stimuli, which is thought to affect both the innate and adaptive immune systems. This essay sought to provide an outline of vitamin D's role in the treatment of tuberculosis. For journal articles, reports, and reliable sources, several databases were searched to compile pertinent information. Additionally, search terms were utilised interchangeably to find pertinent materials. The majority of the literature revealed a connection between vitamin D levels and TB. Furthermore, research has indicated that certain vitamins, including Vitamins C and D, have antimycobacterial capabilities. Despite contradicting data about the relationship between Vitamin D Deficiency (VDD) and the risk of tuberculosis, vitamin D supplementation is still a viable strategy. The analysis of the impact of vitamin D supplementation as a potential therapeutic intervention for TB infection should pay more attention to exploring larger sample sizes and metabolite chemicals.

Keywords

• Antimycobacterial
• Mycobacterium tuberculosis
• Tuberculosis and Vitamin D