Molecules (Aug 2015)

Addition of CFCl3 to Aromatic Aldehydes via in Situ Grignard Reaction

  • Balaka Barkakaty,
  • Bandana Talukdar,
  • Bradley S. Lokitz

DOI
https://doi.org/10.3390/molecules200815098
Journal volume & issue
Vol. 20, no. 8
pp. 15098 – 15107

Abstract

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Synthetic modification of trichlorofluoromethane (CFCl3) to non-volatile and useful fluorinated precursors is a cost-effective and an environmentally benign strategy for the safe consumption/destruction of the ozone depleting potential of the reagent. In this report, we present a novel method for in situ Grignard reaction using magnesium powder and CFCl3 for synthesis of dichlorofluoromethyl aromatic alcohols.

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