Zhongguo shuxue zazhi (Feb 2024)

Skin injury around enterostomy cured by allogeneic platelet-rich plasma: a report of two cases

  • Honglin YAO,
  • Qing QI,
  • Shujun WANG,
  • Shuo SHEN,
  • Jianfeng LUAN,
  • Xianghong YE

DOI
https://doi.org/10.13303/j.cjbt.issn.1004­549x.2024.02.014
Journal volume & issue
Vol. 37, no. 2
pp. 209 – 213

Abstract

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Objective To investigate the feasibility of allogeneic platelet-rich plasma (PRP) for the treatment of skin injury around enterostomy. Methods The treatment process by PRP of 2 patients with skin injury around enterostomy was analyzed, and the PRP for each patient was tested with platelet count, bacteria and 5 growth factors. The clinical efficacy of enteral nutrition support therapy combined with allogeneic PRP was explored through analyzing treatment key points and literature review. Results After cleaning the skin around enterostomy, the patients were treated with PRP once daily for 5 days, adjusted to once every other day, and cure was achieved at 15 and 18 days, respectively. Conclusion Allogeneic PRP is a safe and effective treatment to promote skin injury around enterostomy regeneration in a short time, which can provide a new perspective for clinical.

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