Nature Communications (Oct 2018)

Immune-suppression by OsHV-1 viral infection causes fatal bacteraemia in Pacific oysters

  • Julien de Lorgeril,
  • Aude Lucasson,
  • Bruno Petton,
  • Eve Toulza,
  • Caroline Montagnani,
  • Camille Clerissi,
  • Jeremie Vidal-Dupiol,
  • Cristian Chaparro,
  • Richard Galinier,
  • Jean-Michel Escoubas,
  • Philippe Haffner,
  • Lionel Dégremont,
  • Guillaume M. Charrière,
  • Maxime Lafont,
  • Abigaïl Delort,
  • Agnès Vergnes,
  • Marlène Chiarello,
  • Nicole Faury,
  • Tristan Rubio,
  • Marc A. Leroy,
  • Adeline Pérignon,
  • Denis Régler,
  • Benjamin Morga,
  • Marianne Alunno-Bruscia,
  • Pierre Boudry,
  • Frédérique Le Roux,
  • Delphine Destoumieux-Garzόn,
  • Yannick Gueguen,
  • Guillaume Mitta

DOI
https://doi.org/10.1038/s41467-018-06659-3
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 14

Abstract

Read online

Pacific oyster mortality syndrome is a poorly understood cause of mortality in commercially important oyster species. Here, the authors use multiple infection experiments to show that the syndrome is caused by sequential infection by herpesvirus and opportunistic bacteria.