P327: LOSS OF POLYCOMB REPRESSIVE COMPLEX 2 FUNCTION CAUSES ASPARAGINASE RESISTANCE IN T-ACUTE LYMPHOBLASTIC LEUKAEMIA THROUGH DECREASED WNT PATHWAY ACTIVITY

• Thomas Lefeivre,
• Cosmin Tudose,
• Theodora Grosu,
• Luke Jones,
• Theresa Leon,
• Kieran Wynne,
• Giorgio Oliviero,
• Owen Smith,
• Amélie Trinquand,
• Marc Mansour,
• Colm Ryan,
• Jonathan Bond

Affiliations

Thomas Lefeivre

1 Systems Biology Ireland, Dublin, Ireland

Cosmin Tudose

1 Systems Biology Ireland, Dublin, Ireland

Theodora Grosu

1 Systems Biology Ireland, Dublin, Ireland

Luke Jones

1 Systems Biology Ireland, Dublin, Ireland

Theresa Leon

4 University College London, UCL Cancer Institute, United Kingdom

Kieran Wynne

1 Systems Biology Ireland, Dublin, Ireland

Giorgio Oliviero

1 Systems Biology Ireland, Dublin, Ireland

Owen Smith

1 Systems Biology Ireland, Dublin, Ireland

Amélie Trinquand

6 Children’s Health Ireland (CHI) at Crumlin, Dublin, Ireland

Marc Mansour

4 University College London, UCL Cancer Institute, United Kingdom

Colm Ryan

1 Systems Biology Ireland, Dublin, Ireland

Jonathan Bond

1 Systems Biology Ireland, Dublin, Ireland