P327: LOSS OF POLYCOMB REPRESSIVE COMPLEX 2 FUNCTION CAUSES ASPARAGINASE RESISTANCE IN T-ACUTE LYMPHOBLASTIC LEUKAEMIA THROUGH DECREASED WNT PATHWAY ACTIVITY
Thomas Lefeivre,
Cosmin Tudose,
Theodora Grosu,
Luke Jones,
Theresa Leon,
Kieran Wynne,
Giorgio Oliviero,
Owen Smith,
Amélie Trinquand,
Marc Mansour,
Colm Ryan,
Jonathan Bond
Affiliations
Thomas Lefeivre
1 Systems Biology Ireland, Dublin, Ireland
Cosmin Tudose
1 Systems Biology Ireland, Dublin, Ireland
Theodora Grosu
1 Systems Biology Ireland, Dublin, Ireland
Luke Jones
1 Systems Biology Ireland, Dublin, Ireland
Theresa Leon
4 University College London, UCL Cancer Institute, United Kingdom
Kieran Wynne
1 Systems Biology Ireland, Dublin, Ireland
Giorgio Oliviero
1 Systems Biology Ireland, Dublin, Ireland
Owen Smith
1 Systems Biology Ireland, Dublin, Ireland
Amélie Trinquand
6 Children’s Health Ireland (CHI) at Crumlin, Dublin, Ireland
Marc Mansour
4 University College London, UCL Cancer Institute, United Kingdom
