Diagnostics (Sep 2024)

The Development of a Quantitative Disability Assessment Tool in Patients with Idiopathic Parkinson’s Disease

  • Han Gil Seo,
  • Seo Jung Yun,
  • Yoojin Song,
  • Ho Seok Lee,
  • Dae Hyun Kim,
  • Won Hyuk Chang

DOI
https://doi.org/10.3390/diagnostics14182063
Journal volume & issue
Vol. 14, no. 18
p. 2063

Abstract

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Background/Objectives: The objective of this study was to develop a novel quantitative disability assessment tool for patients with idiopathic Parkinson’s disease (IPD). Methods: A total of 47 patients with IPD were recruited from two hospitals. A specialist in Rehabilitation Medicine utilized the modified Schwab and England Activities of Daily Living Scale (mSEADL) as a reference, conducting a comprehensive medical chart review and an in-depth interview. The novel-developed disability measurement was calculated as ((mSEADL during the on-state) × (time of on-state)) + ((mSEADL during the off-state) × (time of off-state))/(waking time). Additionally, the degree of disability was assessed using the Korean version of the Modified Barthel Index during the on-state. Results: Twenty-four participants (51.1%) exhibited the off-state during waking hours. In patients exhibiting an off-state, the mSEADL score was significantly lower during the off-state than during the on-state (p p Conclusions: The results demonstrated that larger IPD patients exhibited an on–off phenomenon with greater dependency during the off-state. Therefore, the on–off phenomenon should be considered when evaluating disability in patients with IPD, with methods such as the novel-developed disability measurement tool in this study.

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