STRUCTURAL AND FUNCTIONAL CHANGES OF THE PROSTATE GLAND CAUSED BY PYELONEPHRITIS

Abstract

Ultrasonic scanning methods of color ultrasound angiography, histology, morphometry and statistics the peculiarities of hemodynamics have been studied and also parametric and structural-functional changes in the prostate gland in men of mature age under the conditions of the transferred chronic pyelonephritis. Studies of echometric parameters of the prostate gland of men of mature age (first period) who suffered from chronic orchoepididymitis show that its volume increased to (27.5±1.1) сm³ against (21.6±0.5) сm³ in men control group, and weight up to (28.7±1.9) g against (21.9±1.3) g in the control. Probably increases the width, thickness and length of the prostate gland. In men with chronic pyelonephritis the relative area of the glandular component decreases to 57%, and the relative area of the muscular-elastic stroma increases to 43% up 70% and 30% in the control. There are four zones in the prostate gland of mature men: transitional, central, peripheral and anterior. The main analytical reference point in determining these zones on histological preparations is the prostatic part of the male urethra. The most extensive among them is the peripheral zone, which is located around the prostate lobe of the urethra. It occupies about 75% of the prostate gland. Histologically in the prostate gland the number and size of alveolar-tubular glands decreases, some of them are cystically expanded, their lining epithelium flattens, pyknotic nuclei. Epithelial folds and protrusions are preserved in some glands, prostatic nodules and acidophilic secretion are found in the lumens. The described atrophic changes are local in nature. In some glands the prismatic epithelium with clear contours and intensely colored nucleus is preserved.

Keywords

• prostate gland,hemodynamics,histostructure,chronic pyelonephritis.