Nature Communications (Nov 2017)

Region and cell-type resolved quantitative proteomic map of the human heart

  • Sophia Doll,
  • Martina Dreßen,
  • Philipp E. Geyer,
  • Daniel N. Itzhak,
  • Christian Braun,
  • Stefanie A. Doppler,
  • Florian Meier,
  • Marcus-Andre Deutsch,
  • Harald Lahm,
  • Rüdiger Lange,
  • Markus Krane,
  • Matthias Mann

DOI
https://doi.org/10.1038/s41467-017-01747-2
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 13

Abstract

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The human heart is composed of distinct regions and cell types, but relatively little is known about their specific protein composition. Here, the authors present a region- and cell type-specific proteomic map of the healthy human heart, revealing functional differences and potential cell type markers.