Synthesis and Characterization of New Oxazolidin-4-one Derivatives via the Reaction of Various Some Imines with Glycolic Acid

Abstract

New derivatives of 2,3-disubstituted- oxazolidine-4-one were synthesized by cycloaddition reaction of glycolic acid to various imines in anhydrous 1,4-dioxane under dry and reflux conditions. Imines were synthesized by acid–catalyzed thermal condensation of the amino group of aromatic amine and phenylhydrazines with the carbonyl group of aromatic aldehydes and ketones in absolute ethanol. The products were identified by C.H.N content FT-IR and 1HNMR spectra

Keywords

• oxazolindine
• one
• imines
• glycolic acid