Hypolipidemic effect of ethanol extract from Chimonanthus nitens Oliv. leaves in hyperlipidemia rats via activation of the leptin/JAK2/STAT3 pathway

Abstract

Highlights 1. COE improves lipid levels and lipase activities in hyperlipidemic rats. 2. COE ameliorates antioxidant enzyme activities and liver function in hyperlipidemic rats. 3. COE exerts a hypolipidemic effect by activating the leptin/JAK2/STAT3 pathway.

Keywords

• Chimonanthus nitens Oliv. leaf
• Hyperlipidemia
• Leptin/JAK2/STAT3 pathway
• Lipid metabolism
• Oxidative stress