Nature Communications (Feb 2023)

Lipopolysaccharide biosynthesis and traffic in the envelope of the pathogen Brucella abortus

  • Caroline Servais,
  • Victoria Vassen,
  • Audrey Verhaeghe,
  • Nina Küster,
  • Elodie Carlier,
  • Léa Phégnon,
  • Aurélie Mayard,
  • Nicolas Auberger,
  • Stéphane Vincent,
  • Xavier De Bolle

DOI
https://doi.org/10.1038/s41467-023-36442-y
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 13

Abstract

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Pathogenic Brucella abortus, containing a mix of lipopolysaccharides with or without O-antigen, grows its envelope in a unipolar manner. Here, Servais et al, localize the LPS translocation machinery and identify the main O-antigen ligase in Brucella species, shedding light on the basic biology of this organism.