Radiology Case Reports (Nov 2023)

A case of pituitary metastasis discovered when diabetes insipidus developed in a patient 20 years after breast cancer treatment

  • Kotaro Minami, MD,
  • Yutaka Ueno, MD,
  • Yusuke Minamidate, MD,
  • Ken Shigeyama, MD,
  • Kohiro Akita, MD,
  • Keina Terada, MD,
  • Teppaei Kishino, MD,
  • Tomoya Osaka, MD,
  • Kanji Sugiura, MD,
  • Osamu Honda, MD, PhD,
  • Noboru Tanigawa, MD, PhD

Journal volume & issue
Vol. 18, no. 11
pp. 3904 – 3907

Abstract

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The patient was a 52-year-old woman. She had a history of left breast cancer at age 32 years, with no recurrences. She was examined for a feeling of oral dryness and nocturia, and central diabetes insipidus was diagnosed. A mass was seen in the posterior pituitary on magnetic resonance imaging, and multiple pulmonary nodules were seen on computed tomography. Breast cancer metastases were diagnosed in both tissues. Since this patient had no cancer other than the breast cancer treated 20 years earlier, it was difficult to reach a diagnosis of pituitary metastasis with pituitary gland imaging alone. In estrogen receptor-positive breast cancer, there may be recurrences after a long period of time. It may be that recommending a full body examination could be useful in the differential diagnosis of metastasis even in patients who have had a long disease-free period, if they had undergone surgery for breast cancer.

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