A case of pituitary metastasis discovered when diabetes insipidus developed in a patient 20 years after breast cancer treatment

Kotaro Minami, MD; Yutaka Ueno, MD; Yusuke Minamidate, MD; Ken Shigeyama, MD; Kohiro Akita, MD; Keina Terada, MD; Teppaei Kishino, MD; Tomoya Osaka, MD; Kanji Sugiura, MD; Osamu Honda, MD, PhD; Noboru Tanigawa, MD, PhD

Radiology Case Reports (Nov 2023)

A case of pituitary metastasis discovered when diabetes insipidus developed in a patient 20 years after breast cancer treatment

Kotaro Minami, MD,
Yutaka Ueno, MD,
Yusuke Minamidate, MD,
Ken Shigeyama, MD,
Kohiro Akita, MD,
Keina Terada, MD,
Teppaei Kishino, MD,
Tomoya Osaka, MD,
Kanji Sugiura, MD,
Osamu Honda, MD, PhD,
Noboru Tanigawa, MD, PhD

Affiliations

Kotaro Minami, MD: Department of Radiology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka 5731010, Japan
Yutaka Ueno, MD: Corresponding author.; Department of Radiology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka 5731010, Japan
Yusuke Minamidate, MD: Department of Radiology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka 5731010, Japan
Ken Shigeyama, MD: Department of Radiology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka 5731010, Japan
Kohiro Akita, MD: Department of Radiology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka 5731010, Japan
Keina Terada, MD: Department of Radiology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka 5731010, Japan
Teppaei Kishino, MD: Department of Radiology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka 5731010, Japan
Tomoya Osaka, MD: Department of Radiology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka 5731010, Japan
Kanji Sugiura, MD: Department of Radiology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka 5731010, Japan
Osamu Honda, MD, PhD: Department of Radiology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka 5731010, Japan
Noboru Tanigawa, MD, PhD: Department of Radiology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka 5731010, Japan

Journal volume & issue: Vol. 18, no. 11
pp. 3904 – 3907

Abstract

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The patient was a 52-year-old woman. She had a history of left breast cancer at age 32 years, with no recurrences. She was examined for a feeling of oral dryness and nocturia, and central diabetes insipidus was diagnosed. A mass was seen in the posterior pituitary on magnetic resonance imaging, and multiple pulmonary nodules were seen on computed tomography. Breast cancer metastases were diagnosed in both tissues. Since this patient had no cancer other than the breast cancer treated 20 years earlier, it was difficult to reach a diagnosis of pituitary metastasis with pituitary gland imaging alone. In estrogen receptor-positive breast cancer, there may be recurrences after a long period of time. It may be that recommending a full body examination could be useful in the differential diagnosis of metastasis even in patients who have had a long disease-free period, if they had undergone surgery for breast cancer.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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