Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Sweden
Erik Forsell
Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Sweden
Eyal Karin
eCentreClinic, Department of Psychology, Macquarie University, Australia
Robert Johansson
Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet and Department of Psychology, Stockholm University, Sweden
Nils Lindefors
Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Sweden
Viktor Kaldo
Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet and Department of Psychology, Faculty of Health and Life Sciences, Linnaeus University, Sweden
Disorder-specific internet-based cognitive–behavioural therapy (ICBT) is effective for depression, panic disorder and social anxiety. In this benchmarking study, a new, individually tailored, ICBT programme (TAIL) showed effects on depression (n = 284, d = 1.33) that were non-inferior to disorder-specific ICBT for depression in routine care (n = 2358, d = 1.35). However, the hypotheses that TAIL for individuals with social anxiety or panic disorder is inferior to disorder-specific ICBT could not be rejected (social anxiety: TAIL d = 0.74 versus disorder-specific d = 0.81; panic: TAIL d = 1.11 versus disorder-specific d = 1.47). Our findings strengthen the empirical base for TAIL as an alternative to disorder-specific ICBT for depression.