The Relationship between Thyroid Hormones with ST-segment Resolution in Patients with STEMI Who Underwent Primary Percutaneous Intervention

Abstract

Background: Recently, researchers have become more interested in the role of thyroid hormones in acute coronary syndromes. In the present study, the serum levels of thyroid hormones in STEMI patients at the time of hospital admission and the it's correlation in the success rate in primary percutaneous intervention which is depicted in the form of ST-resolution was evaluated. Methods: In this study, 500 patients who underwent primary angioplasty in Shahid Madani Tabriz hospital within early 2016 and late 2017 were included. The participants were divided in two groups: group 1 (decrease in ST-resolution less than 50%) and group 2 (decrease in ST-RESOLUTION more than 50%). Correlations between thyroid hormones, ST resolution, mortality and Major Adverse Cardiovascular Events (MACE) were assessed. Findings: The mean age of the patients was 57.22 ± 11.32 years old while 401 patients (80.2%) were male and 99 patients (19.8%) were female. In 152 patients (30.4%) ST resolution was 50% and less (group 1) and in 348 patients (69.6%) ST-RESOLUTION was more than 50%. No significant correlation was found between TSH and FT3 levels and ST resolution. Also, MACE and thyroid hormones didn’t have any correlation. Conclusion: The finding of the present study showed there was no significant relationship between ST resolution and MACE and FT4, TSH and FT3 levels.

Keywords

• coronary angioplasty
• myocardial infarction
• mortality
• st elevation myocardial infarction
• thyroid hormones