Bioautomation (Dec 2009)
Quasi-Stationary Approximation of a Dynamical Model of MicroRNA Target Regulation. Part II. Application of the QSSA Theorem
Abstract
The QSSA theorem is applied to the dynamical model of microRNA target regulation after special selection of model variables, presented in Part I of this article. On the basis of this theorem the complete model, represented as a system of seven nonlinear ordinary differential equations, is reduced to a degenerate one, comprising only two ordinary differential equations. As a result it is proved that the proteins, produced by miRNAs are identified to play a driving role of the dynamical behaviour of the genetic process investigated, but in post-initial (or quasi-stationary) stage.