Neopterin as а Modern Marker of Inflammation

Abstract

Acute respiratory viral infections are one of the topical problems of pediatrics, due to the high level of morbidity in the pediatric population, a significant incidence of severe and complicated variants of the disease, especially among young children. It is known that respiratory viral infections under the influence of a pathogen is a dysfunction of interferonogenesis. Analyzed the results of scientific investigations devoted to the determination of neopterin concentration in relation to diseases associated with activation mediated by interferon- immune response. The increase in its concentration correlates with the changes of INF-, INF- and is associated with a systemic inflammatory response. Monitoring of the level of neopterin may be useful as a potential marker of the state of antiviral protection in children.

Keywords

• neopterin
• interferon- 
• interferon-