Nature Communications (May 2020)

A common allosteric mechanism regulates homeostatic inactivation of auxin and gibberellin

  • Sayaka Takehara,
  • Shun Sakuraba,
  • Bunzo Mikami,
  • Hideki Yoshida,
  • Hisako Yoshimura,
  • Aya Itoh,
  • Masaki Endo,
  • Nobuhisa Watanabe,
  • Takayuki Nagae,
  • Makoto Matsuoka,
  • Miyako Ueguchi-Tanaka

DOI
https://doi.org/10.1038/s41467-020-16068-0
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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Enzymatic inactivation of gibberellins and auxin, via GA2ox3 and DAO respectively, contributes to hormone homeostasis in plants. Here Takehara et al. show that both enzymes multimerize in a substrate-concentration-dependent manner, and that this multimerization leads to increased enzyme activity.