Infection and Drug Resistance (Apr 2019)

Diffuse multibacillary leprosy patient with Lucio’s phenomenon and positive anticardiolipin antibody misdiagnosed as lupus erythematosus panniculitis in the People’s Republic of China

  • Gao W,
  • Chen Z,
  • Jiang H,
  • Shi Y,
  • Zhang W,
  • Wang H

Journal volume & issue
Vol. Volume 12
pp. 741 – 744

Abstract

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Wei Gao, Zhiming Chen, Haiqin Jiang, Ying Shi, Wenyue Zhang, Hongsheng WangInstitute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Nanjing 210042, People’s Republic of ChinaAbstract: Lucio’s phenomenon (LP) is a special reactional state associated with diffuse multibacillary leprosy; both exhibit a limitative global distribution mainly in Mexico and Central America. We report a case of a 28-year-old female leprosy patient in the People’s Republic of China, together with LP and positive anticardiolipin antibody, characterized by vascular thrombosis and invasion of blood vessel walls by leprosy bacilli, causing extensive skin ulcers and followed by a large number of atrophic scars.Keywords: Leprosy, Lucio’s phenomenon, anticardiolipin antibody

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