PLoS ONE (Jan 2020)

A comparison of the corneal biomechanics in pseudoexfoliation glaucoma, primary open-angle glaucoma and healthy controls using Corvis ST.

  • Zia Sultan Pradhan,
  • Sujit Deshmukh,
  • Shivani Dixit,
  • Shruthi Sreenivasaiah,
  • Sujani Shroff,
  • Sathi Devi,
  • Carroll A B Webers,
  • Harsha Laxmana Rao

DOI
https://doi.org/10.1371/journal.pone.0241296
Journal volume & issue
Vol. 15, no. 10
p. e0241296

Abstract

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PurposeTo compare the corneal biomechanical parameters between pseudoexfoliation glaucoma (PXG), primary open-angle glaucoma (POAG) and healthy controls using Corvis ST.MethodsA prospective, cross-sectional study was conducted which included 132 treatment-naïve eyes which underwent Corvis ST. The study cohort comprised of 44 eyes with PXG, 42 eyes with POAG and 46 healthy controls. Corneal biomechanical parameters, which included corneal velocities, length of corneal applanated surface, deformation amplitude (DA), peak distance and radius of curvature, were compared between the groups using analysis of variance models.ResultsThe 3 groups were demographically similar. The mean IOP was 15.7 ±3 mmHg in the control group, 21.3 ±5 mmHg in the POAG group and 25.8 ±7 mmHg in the PXG group (pConclusionCorneal biomechanical parameters measured on Corvis ST are not different between eyes with PXG, POAG and healthy controls after adjusting for IOP.