Pharmacokinetics of a Modified-Release Dexamphetamine Sulfate Formulation Following Single and Multiple Dosing in Healthy Adults: Comparative Bioavailability with Immediate-Release Dexamphetamine Sulfate, between Strengths, Assessment of Food and Meal Composition Effects

Affiliations

Sandersleben Henrik Uebel-von: 1Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany
Mayer Anke: 2Medical Department, MEDICE Arzneimittel Pütter GmbH & Co. KG, Iserlohn, Germany
Ruhmann Michaela: 2Medical Department, MEDICE Arzneimittel Pütter GmbH & Co. KG, Iserlohn, Germany
Dangel Oliver: 2Medical Department, MEDICE Arzneimittel Pütter GmbH & Co. KG, Iserlohn, Germany
Schütz Helmut: 3BEBAC – Consultancy Services for Bioequivalence and Bioavailability Studies, Vienna, Austria

Abstract

A modified-release dexamphetamine sulfate formulation (DEX-MR) is under development for the treatment of attention-deficit/hyperactivity disorder.

ISSN: 2245-8875 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system: Psychiatry; Philosophy. Psychology. Religion: Psychology
Website: https://sciendo.com/journal/SJCAPP