Nature Communications (Apr 2021)

Detecting local genetic correlations with scan statistics

  • Hanmin Guo,
  • James J. Li,
  • Qiongshi Lu,
  • Lin Hou

DOI
https://doi.org/10.1038/s41467-021-22334-6
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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Genetic correlation analyses give insight on complex disease, yet are limited by oversimplification. Here, the authors present LOGODetect, a method using summary statistics from genome-wide association studies to identify genomic regions with correlation signals across multiple phenotypes.