Nature Communications (Mar 2017)

Barcode extension for analysis and reconstruction of structures

  • Cameron Myhrvold,
  • Michael Baym,
  • Nikita Hanikel,
  • Luvena L Ong,
  • Jonathan S Gootenberg,
  • Peng Yin

DOI
https://doi.org/10.1038/ncomms14698
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 9

Abstract

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Techniques for structural characterization and quantification of DNA origami are still poorly developed, despite advances in other aspects of DNA nanotechnology. Here, the authors combine barcoding and next generation sequencing to simultaneously image and quantify self-assembled DNA nanostructures.