Nature Communications (Jan 2020)

Dopamine transients do not act as model-free prediction errors during associative learning

  • Melissa J. Sharpe,
  • Hannah M. Batchelor,
  • Lauren E. Mueller,
  • Chun Yun Chang,
  • Etienne J. P. Maes,
  • Yael Niv,
  • Geoffrey Schoenbaum

DOI
https://doi.org/10.1038/s41467-019-13953-1
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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Dopamine neurons are proposed to signal the reward prediction error in model-free reinforcement learning algorithms. Here, the authors show that when given during an associative learning task, optogenetic activation of dopamine neurons causes associative, rather than value, learning.